mad cow home or moly bio area or best links

Mouse prion 121-231 alpha carbon coordinates ... Kinemage model
Hamster amyloid H1 side chain coordinates ... Kinemage model
Prion dimer pdb alpha carbon coordinates ... Kinemage model

RasMol versions of models Inouye's amyloid H1... Swiss prion monomer ... Warwicker's dimer

The structure of mouse prion fragment 121-231 was determined from solution NMR. Coordinates kindly provided by Dr. Martin Billeter of the Zurich group on 27 May 97. More graphics are available at his lab's home page. The data are in PDF format as used by the Brookhaven Protein Database.

HEADER    CA-coordinates of the NMR structure of PrP(121-231).
REMARK    May 29, 1997.
REMARK    These coordinates describe a refined mean structure 
REMARK    calculated with a more complete NMR input compared to
REMARK    the structure presented by Riek et al. (Nature 382,
REMARK    180-182, 1996). A publication describing this refined
REMARK    structure is submitted, and the complete set of
REMARK    coordinates is deposited with the Protein Data Bank
REMARK    accession code 1AG2.
ATOM      1  CA  GLY   124     -10.625  12.191   4.609  1.00  1.00
ATOM      2  CA  LEU   125      -8.514  13.845   1.821  1.00  1.00
ATOM      3  CA  GLY   126     -11.828  14.646   0.116  1.00  1.00
ATOM      4  CA  GLY   127     -13.173  11.587  -1.690  1.00  1.00
ATOM      5  CA  TYR   128     -11.752   8.818   0.495  1.00  1.00
ATOM      6  CA  MET   129     -10.899   7.653   4.014  1.00  1.00
ATOM      7  CA  LEU   130      -7.220   8.171   4.816  1.00  1.00
ATOM      8  CA  GLY   131      -7.421   5.757   7.773  1.00  1.00
ATOM      9  CA  SER   132      -5.657   6.939  10.977  1.00  1.00
ATOM     10  CA  ALA   133      -2.936   4.214  10.620  1.00  1.00
ATOM     11  CA  MET   134      -2.793   0.543   9.544  1.00  1.00
ATOM     12  CA  SER   135      -0.370  -2.402   9.798  1.00  1.00
ATOM     13  CA  ARG   136       2.760  -2.863   7.762  1.00  1.00
ATOM     14  CA  PRO   137       1.869  -5.933   5.599  1.00  1.00
ATOM     15  CA  MET   138       4.275  -8.831   5.075  1.00  1.00
ATOM     16  CA  ILE   139       4.304 -10.198   1.523  1.00  1.00
ATOM     17  CA  HIS   140       6.286 -13.003  -0.068  1.00  1.00
ATOM     18  CA  PHE   141       7.427 -11.385  -3.346  1.00  1.00
ATOM     19  CA  GLY   142       8.403 -14.751  -4.961  1.00  1.00
ATOM     20  CA  ASN   143      12.115 -13.773  -4.913  1.00  1.00
ATOM     21  CA  ASP   144      14.027 -13.790  -1.580  1.00  1.00
ATOM     22  CA  TRP   145      15.643 -10.415  -2.190  1.00  1.00
ATOM     23  CA  GLU   146      12.412  -8.701  -3.176  1.00  1.00
ATOM     24  CA  ASP   147      10.962  -9.925   0.157  1.00  1.00
ATOM     25  CA  ARG   148      14.110  -8.622   1.873  1.00  1.00
ATOM     26  CA  TYR   149      13.900  -5.387  -0.188  1.00  1.00
ATOM     27  CA  TYR   150      10.422  -4.614   1.152  1.00  1.00
ATOM     28  CA  ARG   151      11.243  -5.834   4.709  1.00  1.00
ATOM     29  CA  GLU   152      14.448  -3.847   4.933  1.00  1.00
ATOM     30  CA  ASN   153      12.276  -0.844   3.912  1.00  1.00
ATOM     31  CA  MET   154       8.901  -1.385   5.673  1.00  1.00
ATOM     32  CA  TYR   155       9.952   1.227   8.313  1.00  1.00
ATOM     33  CA  ARG   156      10.343   4.031   5.716  1.00  1.00
ATOM     34  CA  TYR   157       7.170   2.932   3.860  1.00  1.00
ATOM     35  CA  PRO   158       3.547   4.109   4.508  1.00  1.00
ATOM     36  CA  ASN   159       1.795   3.641   7.869  1.00  1.00
ATOM     37  CA  GLN   160      -1.466   5.123   6.481  1.00  1.00
ATOM     38  CA  VAL   161      -3.245   4.727   3.103  1.00  1.00
ATOM     39  CA  TYR   162      -6.394   6.071   1.466  1.00  1.00
ATOM     40  CA  TYR   163      -9.273   3.678   0.865  1.00  1.00
ATOM     41  CA  ARG   164     -12.479   3.926  -1.145  1.00  1.00
ATOM     42  CA  PRO   165     -14.631   1.312   0.705  1.00  1.00
ATOM     43  CA  VAL   166     -15.694  -1.858  -1.148  1.00  1.00
ATOM     44  CA  ASP   167     -19.251  -1.526   0.134  1.00  1.00
ATOM     45  CA  GLN   168     -20.607  -3.114  -3.103  1.00  1.00
ATOM     46  CA  TYR   169     -18.180  -2.875  -6.082  1.00  1.00
ATOM     47  CA  SER   170     -16.394  -6.209  -5.253  1.00  1.00
ATOM     48  CA  ASN   171     -12.921  -7.238  -6.533  1.00  1.00
ATOM     49  CA  GLN   172     -10.089  -5.664  -4.521  1.00  1.00
ATOM     50  CA  ASN   173      -8.132  -4.523  -7.589  1.00  1.00
ATOM     51  CA  ASN   174     -11.028  -2.215  -8.601  1.00  1.00
ATOM     52  CA  PHE   175     -10.760  -0.101  -5.431  1.00  1.00
ATOM     53  CA  VAL   176      -6.988  -0.628  -5.050  1.00  1.00
ATOM     54  CA  HIS   177      -6.833   1.478  -8.278  1.00  1.00
ATOM     55  CA  ASP   178      -7.340   4.737  -6.307  1.00  1.00
ATOM     56  CA  CYS   179      -4.874   3.416  -3.705  1.00  1.00
ATOM     57  CA  VAL   180      -1.930   2.261  -5.872  1.00  1.00
ATOM     58  CA  ASN   181      -2.600   5.595  -7.620  1.00  1.00
ATOM     59  CA  ILE   182      -3.195   8.274  -4.989  1.00  1.00
ATOM     60  CA  THR   183      -1.644   6.676  -1.872  1.00  1.00
ATOM     61  CA  ILE   184       1.556   5.965  -3.838  1.00  1.00
ATOM     62  CA  LYS   185       1.571   9.573  -5.069  1.00  1.00
ATOM     63  CA  GLN   186       0.901  10.867  -1.547  1.00  1.00
ATOM     64  CA  HIS   187       3.744   8.700  -0.147  1.00  1.00
ATOM     65  CA  THR   188       6.142   9.904  -2.848  1.00  1.00
ATOM     66  CA  VAL   189       5.365  13.627  -3.450  1.00  1.00
ATOM     67  CA  THR   190       4.600  14.367   0.180  1.00  1.00
ATOM     68  CA  THR   191       7.606  12.370   1.520  1.00  1.00
ATOM     69  CA  THR   192      10.091  13.683  -1.095  1.00  1.00
ATOM     70  CA  THR   193       8.943  17.153   0.062  1.00  1.00
ATOM     71  CA  LYS   194      11.107  16.628   3.269  1.00  1.00
ATOM     72  CA  GLY   195      14.023  15.235   1.165  1.00  1.00
ATOM     73  CA  GLU   196      13.181  11.504   1.133  1.00  1.00
ATOM     74  CA  ASN   197      13.297   9.873  -2.307  1.00  1.00
ATOM     75  CA  PHE   198      11.857   6.493  -3.229  1.00  1.00
ATOM     76  CA  THR   199      13.266   5.119  -6.488  1.00  1.00
ATOM     77  CA  GLU   200      11.131   3.566  -9.221  1.00  1.00
ATOM     78  CA  THR   201      11.978   0.212  -7.552  1.00  1.00
ATOM     79  CA  ASP   202      11.005   1.533  -4.063  1.00  1.00
ATOM     80  CA  VAL   203       7.659   2.665  -5.560  1.00  1.00
ATOM     81  CA  LYS   204       7.076  -0.700  -7.386  1.00  1.00
ATOM     82  CA  MET   205       7.765  -2.509  -4.103  1.00  1.00
ATOM     83  CA  MET   206       5.306  -0.140  -2.349  1.00  1.00
ATOM     84  CA  GLU   207       2.539  -1.128  -4.874  1.00  1.00
ATOM     85  CA  ARG   208       2.327  -4.564  -3.256  1.00  1.00
ATOM     86  CA  VAL   209       2.274  -3.083   0.230  1.00  1.00
ATOM     87  CA  VAL   210      -0.389  -0.465  -0.666  1.00  1.00
ATOM     88  CA  GLU   211      -2.761  -3.051  -2.265  1.00  1.00
ATOM     89  CA  GLN   212      -2.336  -5.027   0.977  1.00  1.00
ATOM     90  CA  MET   213      -2.648  -2.082   3.473  1.00  1.00
ATOM     91  CA  CYS   214      -5.812  -0.686   1.832  1.00  1.00
ATOM     92  CA  VAL   215      -7.407  -4.105   2.457  1.00  1.00
ATOM     93  CA  THR   216      -5.463  -4.757   5.780  1.00  1.00
ATOM     94  CA  GLN   217      -7.486  -1.722   7.003  1.00  1.00
ATOM     95  CA  TYR   218     -11.081  -2.516   5.833  1.00  1.00
ATOM     96  CA  GLN   219     -10.384  -6.330   6.145  1.00  1.00
ATOM     97  CA  LYS   220     -12.447  -5.991   9.350  1.00  1.00
ATOM     98  CA  GLU   221     -15.342  -6.629   6.910  1.00  1.00
ATOM     99  CA  SER   222     -13.454  -7.591   3.704  1.00  1.00
ATOM    100  CA  GLN   223     -11.818 -10.752   5.116  1.00  1.00
ATOM    101  CA  ALA   224     -14.944 -12.077   3.308  1.00  1.00
ATOM    102  CA  TYR   225     -13.379 -10.890  -0.018  1.00  1.00
ATOM    103  CA  TYR   226      -9.556 -11.078   0.295  1.00  1.00
END

Proposed H1 model of Dr. Hideyo Inouye. Coordinates kindly provided on 11 Mar 1997. Note that these pdf coordinates also show the side chain atoms. The suggested structure is a hairpin loop.

ATOM      1  N   MET     1       7.802   4.478  14.949  1.00  0.00
ATOM      2  CA  MET     1       7.440   3.636  13.795  1.00  0.00
ATOM      3  C   MET     1       7.944   4.370  12.576  1.00  0.00
ATOM      4  O   MET     1       7.966   5.589  12.607  1.00  0.00
ATOM      5  CB  MET     1       5.916   3.463  13.766  1.00  0.00
ATOM      6  CG  MET     1       5.350   2.606  12.624  1.00  0.00
ATOM      7  SD  MET     1       3.559   2.502  12.698  1.00  0.00
ATOM      8  CE  MET     1       3.271   1.540  11.200  1.00  0.00
ATOM      9  H1  MET     1       7.461   4.057  15.832  1.00  0.00
ATOM     10  H2  MET     1       8.831   4.614  14.977  1.00  0.00
ATOM     11  H3  MET     1       7.378   5.412  14.791  1.00  0.00
ATOM     12  N   LYS     2       8.381   3.615  11.563  1.00  0.00
ATOM     13  CA  LYS     2       8.769   4.265  10.317  1.00  0.00
ATOM     14  C   LYS     2       8.329   3.375   9.163  1.00  0.00
ATOM     15  O   LYS     2       8.449   2.169   9.271  1.00  0.00
ATOM     16  CB  LYS     2      10.292   4.492  10.314  1.00  0.00
ATOM     17  CG  LYS     2      10.964   4.308   8.953  1.00  0.00
ATOM     18  CD  LYS     2      12.236   3.458   9.024  1.00  0.00
ATOM     19  CE  LYS     2      12.551   2.790   7.691  1.00  0.00
ATOM     20  NZ  LYS     2      13.803   2.024   7.808  1.00  0.00
ATOM     21  H   LYS     2       8.379   2.615  11.598  1.00  0.00
ATOM     22  HZ1 LYS     2      14.010   1.552   6.909  1.00  0.00
ATOM     23  HZ2 LYS     2      14.595   2.665   8.041  1.00  0.00
ATOM     24  HZ3 LYS     2      13.703   1.312   8.557  1.00  0.00
ATOM     25  N   HIS     3       8.052   3.973   7.880  1.00  0.00
ATOM     26  CA  HIS     3       7.474   3.160   6.795  1.00  0.00
ATOM     27  C   HIS     3       7.853   3.776   5.466  1.00  0.00
ATOM     28  O   HIS     3       7.884   4.993   5.355  1.00  0.00
ATOM     29  CB  HIS     3       5.946   3.100   6.957  1.00  0.00
ATOM     30  CG  HIS     3       5.263   3.221   5.620  1.00  0.00
ATOM     31  ND1 HIS     3       3.944   3.463   5.471  1.00  0.00
ATOM     32  CD2 HIS     3       5.861   3.131   4.359  1.00  0.00
ATOM     33  CE1 HIS     3       3.701   3.526   4.123  1.00  0.00
ATOM     34  NE2 HIS     3       4.885   3.324   3.452  1.00  0.00
ATOM     35  H   HIS     3       8.028   4.964   7.784  1.00  0.00
ATOM     36  HD1 HIS     3       3.265   3.571   6.176  1.00  0.00
ATOM     37  N   MET     4       8.322   3.244   4.659  1.00  0.00
ATOM     38  CA  MET     4       8.666   3.867   3.386  1.00  0.00
ATOM     39  C   MET     4       8.348   2.883   2.270  1.00  0.00
ATOM     40  O   MET     4       8.683   1.721   2.404  1.00  0.00
ATOM     41  CB  MET     4      10.156   4.253   3.411  1.00  0.00
ATOM     42  CG  MET     4      10.971   3.769   2.213  1.00  0.00
ATOM     43  SD  MET     4      12.712   4.231   2.357  1.00  0.00
ATOM     44  CE  MET     4      13.234   3.654   0.739  1.00  0.00
ATOM     45  H   MET     4       8.387   2.250   4.731  1.00  0.00
ATOM     46  N   ALA     5       7.692   3.407   1.216  1.00  0.00
ATOM     47  CA  ALA     5       7.381   2.682  -0.024  1.00  0.00
ATOM     48  C   ALA     5       6.858   3.744  -0.972  1.00  0.00
ATOM     49  O   ALA     5       6.203   4.669  -0.519  1.00  0.00
ATOM     50  CB  ALA     5       6.302   1.605   0.184  1.00  0.00
ATOM     51  H   ALA     5       7.381   4.355   1.238  1.00  0.00
ATOM     52  N   GLY     6       7.274   3.661  -2.233  1.00  0.00
ATOM     53  CA  GLY     6       7.589   4.911  -2.932  1.00  0.00
ATOM     54  C   GLY     6       6.379   5.656  -3.461  1.00  0.00
ATOM     55  O   GLY     6       5.957   5.473  -4.600  1.00  0.00
ATOM     56  H   GLY     6       7.284   2.789  -2.723  1.00  0.00
ATOM     57  N   ALA     7       5.855   6.495  -2.553  1.00  0.00
ATOM     58  CA  ALA     7       4.499   7.037  -2.691  1.00  0.00
ATOM     59  C   ALA     7       3.435   5.950  -2.905  1.00  0.00
ATOM     60  O   ALA     7       3.737   4.813  -3.228  1.00  0.00
ATOM     61  CB  ALA     7       4.409   8.088  -3.811  1.00  0.00
ATOM     62  H   ALA     7       6.369   6.619  -1.702  1.00  0.00
ATOM     63  N   ALA     8       2.164   6.321  -2.728  1.00  0.00
ATOM     64  CA  ALA     8       1.785   6.990  -1.492  1.00  0.00
ATOM     65  C   ALA     8       1.202   5.931  -0.573  1.00  0.00
ATOM     66  O   ALA     8       1.063   4.780  -0.972  1.00  0.00
ATOM     67  CB  ALA     8       0.737   8.068  -1.769  1.00  0.00
ATOM     68  H   ALA     8       1.490   5.751  -3.206  1.00  0.00
ATOM     69  N   ALA     9       0.880   6.348   0.655  1.00  0.00
ATOM     70  CA  ALA     9       0.315   5.406   1.621  1.00  0.00
ATOM     71  C   ALA     9      -0.197   6.180   2.808  1.00  0.00
ATOM     72  O   ALA     9      -0.127   7.405   2.819  1.00  0.00
ATOM     73  CB  ALA     9       1.371   4.409   2.119  1.00  0.00
ATOM     74  H   ALA     9       0.966   7.305   0.936  1.00  0.00
ATOM     75  N   ALA    10      -0.697   5.433   3.801  1.00  0.00
ATOM     76  CA  ALA    10      -1.162   6.092   5.008  1.00  0.00
ATOM     77  C   ALA    10      -0.660   5.349   6.232  1.00  0.00
ATOM     78  O   ALA    10      -0.516   4.132   6.213  1.00  0.00
ATOM     79  CB  ALA    10      -2.693   6.120   5.024  1.00  0.00
ATOM     80  H   ALA    10      -0.731   4.435   3.748  1.00  0.00
ATOM     81  N   GLY    11      -0.375   6.115   7.296  1.00  0.00
ATOM     82  CA  GLY    11       0.046   5.444   8.527  1.00  0.00
ATOM     83  C   GLY    11      -0.316   6.257   9.741  1.00  0.00
ATOM     84  O   GLY    11      -0.144   7.469   9.744  1.00  0.00
ATOM     85  H   GLY    11      -0.437   7.115   7.264  1.00  0.00
ATOM     86  N   ALA    12      -0.833   5.543  10.741  1.00  0.00
ATOM     87  CA  ALA    12      -1.282   6.227  11.941  1.00  0.00
ATOM     88  C   ALA    12      -0.887   5.421  13.159  1.00  0.00
ATOM     89  O   ALA    12      -1.008   4.202  13.156  1.00  0.00
ATOM     90  CB  ALA    12      -2.806   6.379  11.908  1.00  0.00
ATOM     91  H   ALA    12      -0.909   4.546  10.688  1.00  0.00
ATOM     92  N   VAL    13      -0.373   6.145  14.171  1.00  0.00
ATOM     93  CA  VAL    13       0.077   5.492  15.404  1.00  0.00
ATOM     94  C   VAL    13      -0.369   6.365  16.550  1.00  0.00
ATOM     95  O   VAL    13      -0.199   7.578  16.489  1.00  0.00
ATOM     96  CB  VAL    13       1.617   5.340  15.440  1.00  0.00
ATOM     97  CG1 VAL    13       2.117   4.694  16.741  1.00  0.00
ATOM     98  CG2 VAL    13       2.144   4.569  14.234  1.00  0.00
ATOM     99  H   VAL    13      -0.333   7.145  14.150  1.00  0.00
ATOM    100  N   VAL    14      -0.974   5.699  17.533  1.00  0.00
ATOM    101  CA  VAL    14      -1.406   6.335  18.764  1.00  0.00
ATOM    102  C   VAL    14      -0.922   5.422  19.898  1.00  0.00
ATOM    103  O   VAL    14      -0.594   4.266  19.618  1.00  0.00
ATOM    104  CB  VAL    14      -2.947   6.506  18.748  1.00  0.00
ATOM    105  CG1 VAL    14      -3.462   7.255  19.972  1.00  0.00
ATOM    106  CG2 VAL    14      -3.443   7.211  17.475  1.00  0.00
ATOM    107  OXT VAL    14      -0.836   5.855  21.041  1.00  0.00
ATOM    108  H   VAL    14      -1.002   4.700  17.585  1.00  0.00
END

Mouse prion dimer alpha carbon coordinates125-231 kindly provided by Dr. James Warwicker on 23 May 97. The disulphide bond is also included. The data is based on the Swiss NMR data plus a prediction that 109-122 fold horizontlly across an exposed apolar surface as an alpha helix. The dimer is displayed in fig. 2a of BBRC (1997) 232, 508-512. It may play an important role in the species barrier.

ATOM      1  CA  LEU A 125       4.510   2.518  21.519  1.00  0.00
ATOM      2  CA  GLY A 126       7.513   3.959  23.390  1.00  0.00
ATOM      3  CA  GLY A 127       5.606   6.110  25.905  1.00  0.00
ATOM      4  CA  TYR A 128       4.058   7.718  22.805  1.00  0.00
ATOM      5  CA  MET A 129       1.168   6.671  20.539  1.00  0.00
ATOM      6  CA  LEU A 130       4.247   5.970  18.389  1.00  0.00
ATOM      7  CA  GLY A 131       1.763   7.169  15.746  1.00  0.00
ATOM      8  CA  SER A 132       1.381   7.259  11.946  1.00  0.00
ATOM      9  CA  ALA A 133       1.865   6.545   8.225  1.00  0.00
ATOM     10  CA  MET A 134       2.886   8.456   5.079  1.00  0.00
ATOM     11  CA  SER A 135       3.920   8.338   1.403  1.00  0.00
ATOM     12  CA  ARG A 136       6.844  10.760   0.977  1.00  0.00
ATOM     13  CA  PRO A 137       9.596  13.332   1.612  1.00  0.00
ATOM     14  CA  MET A 138      12.023  13.952  -1.272  1.00  0.00
ATOM     15  CA  ILE A 139      15.198  15.781  -0.195  1.00  0.00
ATOM     16  CA  HIS A 140      18.515  16.126  -2.058  1.00  0.00
ATOM     17  CA  PHE A 141      19.924  18.743   0.342  1.00  0.00
ATOM     18  CA  GLY A 142      19.605  21.253  -2.520  1.00  0.00
ATOM     19  CA  ASN A 143      21.512  19.102  -5.036  1.00  0.00
ATOM     20  CA  ASP A 144      19.432  17.671  -7.902  1.00  0.00
ATOM     21  CA  TRP A 145      21.581  14.514  -7.972  1.00  0.00
ATOM     22  CA  GLU A 146      23.398  13.273  -4.849  1.00  0.00
ATOM     23  CA  ASP A 147      19.586  13.150  -4.644  1.00  0.00
ATOM     24  CA  ARG A 148      17.472  11.315  -7.243  1.00  0.00
ATOM     25  CA  TYR A 149      20.203   9.276  -5.517  1.00  0.00
ATOM     26  CA  TYR A 150      18.380   9.647  -2.181  1.00  0.00
ATOM     27  CA  ARG A 151      15.840   7.871  -4.414  1.00  0.00
ATOM     28  CA  GLU A 152      18.204   4.959  -5.138  1.00  0.00
ATOM     29  CA  ASN A 153      19.566   4.188  -1.653  1.00  0.00
ATOM     30  CA  MET A 154      15.816   3.647  -1.172  1.00  0.00
ATOM     31  CA  TYR A 155      13.515   0.597  -1.227  1.00  0.00
ATOM     32  CA  ARG A 156      15.495   0.550   2.040  1.00  0.00
ATOM     33  CA  TYR A 157      13.498   3.538   3.334  1.00  0.00
ATOM     34  CA  PRO A 158      10.882   2.542   5.934  1.00  0.00
ATOM     35  CA  ASN A 159       7.487   4.253   6.303  1.00  0.00
ATOM     36  CA  GLN A 160       6.768   4.866  10.005  1.00  0.00
ATOM     37  CA  VAL A 161       5.958   7.397  12.749  1.00  0.00
ATOM     38  CA  TYR A 162       6.391   8.791  16.279  1.00  0.00
ATOM     39  CA  TYR A 163       5.262  11.370  18.861  1.00  0.00
ATOM     40  CA  ARG A 164       2.956  13.310  21.208  1.00  0.00
ATOM     41  CA  PRO A 165      -0.406  14.193  22.795  1.00  0.00
ATOM     42  CA  VAL A 166       0.781  17.528  24.231  1.00  0.00
ATOM     43  CA  ASP A 167       2.298  17.817  27.725  1.00  0.00
ATOM     44  CA  GLN A 168       4.912  18.813  25.125  1.00  0.00
ATOM     45  CA  TYR A 169       7.113  21.456  26.787  1.00  0.00
ATOM     46  CA  SER A 170       9.869  23.889  27.826  1.00  0.00
ATOM     47  CA  ASN A 171       8.141  24.307  24.445  1.00  0.00
ATOM     48  CA  GLN A 172      11.340  23.723  22.440  1.00  0.00
ATOM     49  CA  ASN A 173      12.670  20.144  22.301  1.00  0.00
ATOM     50  CA  ASN A 174       9.133  18.768  21.862  1.00  0.00
ATOM     51  CA  PHE A 175      12.178  17.937  19.710  1.00  0.00
ATOM     52  CA  VAL A 176      14.642  16.381  17.241  1.00  0.00
ATOM     53  CA  HIS A 177      14.208  14.142  20.305  1.00  0.00
ATOM     54  CA  ASP A 178      13.457  10.428  20.791  1.00  0.00
ATOM     55  CA  CYS A 179      11.342  10.901  17.645  1.00  0.00
ATOM     56  CB  CYS A 179      10.610  12.228  17.442  1.00  0.00
ATOM     57  SG  CYS A 179       9.011  12.062  16.631  1.00  0.00
ATOM     58  CA  VAL A 180      14.158  10.784  15.067  1.00  0.00
ATOM     59  CA  ASN A 181      16.065   7.918  16.724  1.00  0.00
ATOM     60  CA  ILE A 182      12.658   6.376  17.508  1.00  0.00
ATOM     61  CA  THR A 183       9.844   5.862  14.978  1.00  0.00
ATOM     62  CA  ILE A 184      12.687   4.519  12.810  1.00  0.00
ATOM     63  CA  LYS A 185      14.435   2.479  15.526  1.00  0.00
ATOM     64  CA  GLN A 186      11.071   0.947  14.565  1.00  0.00
ATOM     65  CA  HIS A 187       8.621   1.330  11.659  1.00  0.00
ATOM     66  CA  THR A 188      11.681  -0.750  12.607  1.00  0.00
ATOM     67  CA  VAL A 189       8.638  -2.620  13.962  1.00  0.00
ATOM     68  CA  THR A 190       5.503  -2.956  11.806  1.00  0.00
ATOM     69  CA  THR A 191       8.101  -3.581   9.076  1.00  0.00
ATOM     70  CA  THR A 192       9.849  -6.292  11.122  1.00  0.00
ATOM     71  CA  THR A 193       6.570  -8.251  11.112  1.00  0.00
ATOM     72  CA  LYS A 194       5.344  -8.582   7.509  1.00  0.00
ATOM     73  CA  GLY A 195       9.151  -8.326   7.706  1.00  0.00
ATOM     74  CA  GLU A 196      11.397  -5.660   6.144  1.00  0.00
ATOM     75  CA  ASN A 197      13.257  -2.557   7.371  1.00  0.00
ATOM     76  CA  PHE A 198      16.536  -0.598   7.381  1.00  0.00
ATOM     77  CA  THR A 199      18.762   1.803   5.414  1.00  0.00
ATOM     78  CA  GLU A 200      20.391   5.217   5.948  1.00  0.00
ATOM     79  CA  THR A 201      18.757   6.972   2.974  1.00  0.00
ATOM     80  CA  ASP A 202      15.133   5.871   3.468  1.00  0.00
ATOM     81  CA  VAL A 203      13.903   6.696   6.989  1.00  0.00
ATOM     82  CA  LYS A 204      16.580   9.421   6.944  1.00  0.00
ATOM     83  CA  MET A 205      14.588  10.686   3.941  1.00  0.00
ATOM     84  CA  MET A 206      11.191   9.545   5.262  1.00  0.00
ATOM     85  CA  GLU A 207      12.544  10.807   8.604  1.00  0.00
ATOM     86  CA  ARG A 208      13.387  14.351   7.454  1.00  0.00
ATOM     87  CA  VAL A 209      10.230  12.930   5.838  1.00  0.00
ATOM     88  CA  VAL A 210       8.768  11.894   9.212  1.00  0.00
ATOM     89  CA  GLU A 211      11.028  14.392  11.014  1.00  0.00
ATOM     90  CA  GLN A 212       8.977  16.742   8.809  1.00  0.00
ATOM     91  CA  MET A 213       6.657  14.222  10.498  1.00  0.00
ATOM     92  CA  CYS A 214       9.219  13.687  13.280  1.00  0.00
ATOM     93  SG  CYS A 214       8.842  12.105  14.598  1.00  0.00
ATOM     94  CB  CYS A 214       8.525  13.782  14.026  1.00  0.00
ATOM     95  CA  VAL A 215      10.584  17.137  14.193  1.00  0.00
ATOM     96  CA  THR A 216       7.524  17.062  11.909  1.00  0.00
ATOM     97  CA  GLN A 217       6.251  15.054  14.899  1.00  0.00
ATOM     98  CA  TYR A 218       4.697  17.288  17.579  1.00  0.00
ATOM     99  CA  GLN A 219       3.076  20.646  16.753  1.00  0.00
ATOM    100  CA  LEU B 125      -6.382  10.652  -1.862  0.00  0.00
ATOM    101  CA  GLY B 126      -6.901  14.232  -3.181  0.00  0.00
ATOM    102  CA  GLY B 127      -3.842  14.409  -5.440  0.00  0.00
ATOM    103  CA  TYR B 128      -1.920  13.557  -2.257  0.00  0.00
ATOM    104  CA  MET B 129      -1.196  10.227  -0.472  0.00  0.00
ATOM    105  CA  LEU B 130      -3.793  11.901   1.785  0.00  0.00
ATOM    106  CA  GLY B 131      -1.587  10.141   4.367  0.00  0.00
ATOM    107  CA  SER B 132      -1.620   9.211   8.074  0.00  0.00
ATOM    108  CA  ALA B 133      -2.799   8.520  11.641  0.00  0.00
ATOM    109  CA  MET B 134      -2.195   9.894  15.148  0.00  0.00
ATOM    110  CA  SER B 135      -3.236   9.999  18.822  0.00  0.00
ATOM    111  CA  ARG B 136      -3.141  13.680  19.919  0.00  0.00
ATOM    112  CA  PRO B 137      -2.731  17.500  19.987  0.00  0.00
ATOM    113  CA  MET B 138      -3.964  19.293  23.136  0.00  0.00
ATOM    114  CA  ILE B 139      -4.353  23.096  22.678  0.00  0.00
ATOM    115  CA  HIS B 140      -6.249  25.623  24.857  0.00  0.00
ATOM    116  CA  PHE B 141      -4.838  28.708  23.084  0.00  0.00
ATOM    117  CA  GLY B 142      -2.930  29.409  26.299  0.00  0.00
ATOM    118  CA  ASN B 143      -5.989  29.232  28.559  0.00  0.00
ATOM    119  CA  ASP B 144      -6.107  26.220  30.936  0.00  0.00
ATOM    120  CA  TRP B 145      -9.885  26.085  30.645  0.00  0.00
ATOM    121  CA  GLU B 146     -11.679  27.371  27.526  0.00  0.00
ATOM    122  CA  ASP B 147      -9.456  24.282  26.968  0.00  0.00
ATOM    123  CA  ARG B 148      -9.846  21.054  29.011  0.00  0.00
ATOM    124  CA  TYR B 149     -12.941  22.358  27.204  0.00  0.00
ATOM    125  CA  TYR B 150     -11.256  21.708  23.837  0.00  0.00
ATOM    126  CA  ARG B 151     -11.311  18.239  25.494  0.00  0.00
ATOM    127  CA  GLU B 152     -15.084  18.302  25.905  0.00  0.00
ATOM    128  CA  ASN B 153     -16.204  19.563  22.473  0.00  0.00
ATOM    129  CA  MET B 154     -14.321  16.329  21.577  0.00  0.00
ATOM    130  CA  TYR B 155     -15.327  12.694  20.898  0.00  0.00
ATOM    131  CA  ARG B 156     -16.271  14.834  17.861  0.00  0.00
ATOM    132  CA  TYR B 157     -12.610  15.210  16.937  0.00  0.00
ATOM    133  CA  PRO B 158     -11.582  12.996  13.984  0.00  0.00
ATOM    134  CA  ASN B 159      -8.159  11.342  13.621  0.00  0.00
ATOM    135  CA  GLN B 160      -6.919  11.783  10.035  0.00  0.00
ATOM    136  CA  VAL B 161      -4.205  13.101   7.714  0.00  0.00
ATOM    137  CA  TYR B 162      -3.063  14.891   4.534  0.00  0.00
ATOM    138  CA  TYR B 163      -0.133  15.953   2.352  0.00  0.00
ATOM    139  CA  ARG B 164       2.986  15.657   0.186  0.00  0.00
ATOM    140  CA  PRO B 165       5.848  13.762  -1.512  0.00  0.00
ATOM    141  CA  VAL B 166       7.871  16.917  -2.235  0.00  0.00
ATOM    142  CA  ASP B 167       7.490  18.923  -5.477  0.00  0.00
ATOM    143  CA  GLN B 168       6.463  21.135  -2.524  0.00  0.00
ATOM    144  CA  TYR B 169       7.352  24.738  -3.499  0.00  0.00
ATOM    145  CA  SER B 170       7.686  28.552  -3.852  0.00  0.00
ATOM    146  CA  ASN B 171       8.759  26.810  -0.616  0.00  0.00
ATOM    147  CA  GLN B 172       6.193  28.675   1.530  0.00  0.00
ATOM    148  CA  ASN B 173       2.573  27.625   1.160  0.00  0.00
ATOM    149  CA  ASN B 174       3.592  23.909   1.039  0.00  0.00
ATOM    150  CA  PHE B 175       0.913  25.480   3.272  0.00  0.00
ATOM    151  CA  VAL B 176      -2.012  26.105   5.639  0.00  0.00
ATOM    152  CA  HIS B 177      -3.235  24.995   2.207  0.00  0.00
ATOM    153  CA  ASP B 178      -5.649  22.310   1.017  0.00  0.00
ATOM    154  CA  CYS B 179      -4.278  20.332   3.998  0.00  0.00
ATOM    155  CB  CYS B 179      -2.814  20.485   4.364  0.00  0.00
ATOM    156  SG  CYS B 179      -2.050  18.963   4.989  0.00  0.00
ATOM    157  CA  VAL B 180      -6.297  22.061   6.753  0.00  0.00
ATOM    158  CA  ASN B 181      -9.549  22.209   4.797  0.00  0.00
ATOM    159  CA  ILE B 182      -8.631  18.718   3.460  0.00  0.00
ATOM    160  CA  THR B 183      -7.558  15.714   5.603  0.00  0.00
ATOM    161  CA  ILE B 184     -10.517  16.821   7.745  0.00  0.00
ATOM    162  CA  LYS B 185     -12.932  17.512   4.881  0.00  0.00
ATOM    163  CA  GLN B 186     -12.186  13.752   5.260  0.00  0.00
ATOM    164  CA  HIS B 187     -10.663  11.496   7.961  0.00  0.00
ATOM    165  CA  THR B 188     -14.057  12.901   6.938  0.00  0.00
ATOM    166  CA  VAL B 189     -13.566   9.612   5.016  0.00  0.00
ATOM    167  CA  THR B 190     -12.126   6.521   6.795  0.00  0.00
ATOM    168  CA  THR B 191     -14.425   7.751   9.592  0.00  0.00
ATOM    169  CA  THR B 192     -17.425   7.931   7.268  0.00  0.00
ATOM    170  CA  THR B 193     -16.981   4.158   6.648  0.00  0.00
ATOM    171  CA  LYS B 194     -16.817   2.342  10.015  0.00  0.00
ATOM    172  CA  GLY B 195     -18.898   5.576  10.201  0.00  0.00
ATOM    173  CA  GLU B 196     -18.302   8.654  12.395  0.00  0.00
ATOM    174  CA  ASN B 197     -16.886  12.175  11.896  0.00  0.00
ATOM    175  CA  PHE B 198     -17.329  15.948  12.516  0.00  0.00
ATOM    176  CA  THR B 199     -16.965  18.784  15.059  0.00  0.00
ATOM    177  CA  GLU B 200     -15.226  22.178  15.273  0.00  0.00
ATOM    178  CA  THR B 201     -13.126  21.365  18.351  0.00  0.00
ATOM    179  CA  ASP B 202     -11.757  17.907  17.355  0.00  0.00
ATOM    180  CA  VAL B 203     -10.058  18.030  13.939  0.00  0.00
ATOM    181  CA  LYS B 204      -9.543  21.759  14.693  0.00  0.00
ATOM    182  CA  MET B 205      -7.613  20.367  17.682  0.00  0.00
ATOM    183  CA  MET B 206      -6.340  17.215  15.889  0.00  0.00
ATOM    184  CA  GLU B 207      -5.874  19.631  12.952  0.00  0.00
ATOM    185  CA  ARG B 208      -3.707  22.172  14.770  0.00  0.00
ATOM    186  CA  VAL B 209      -3.056  18.525  15.829  0.00  0.00
ATOM    187  CA  VAL B 210      -2.689  17.350  12.212  0.00  0.00
ATOM    188  CA  GLU B 211      -1.937  20.940  11.080  0.00  0.00
ATOM    189  CA  GLN B 212       0.949  20.277  13.470  0.00  0.00
ATOM    190  CA  MET B 213       0.524  17.248  11.171  0.00  0.00
ATOM    191  CA  CYS B 214      -1.198  19.482   8.576  0.00  0.00
ATOM    192  SG  CYS B 214      -2.094  18.491   6.975  0.00  0.00
ATOM    193  CB  CYS B 214      -0.638  19.115   7.800  0.00  0.00
ATOM    194  CA  VAL B 215       0.762  22.754   8.402  0.00  0.00
ATOM    195  CA  THR B 216       2.350  19.852  10.359  0.00  0.00
ATOM    196  CA  GLN B 217       1.808  18.192   6.965  0.00  0.00
ATOM    197  CA  TYR B 218       4.733  18.729   4.590  0.00  0.00
ATOM    198  CA  GLN B 219       8.271  19.245   5.842  0.00  0.00
END

mad cow home or moly bio area or best links