InitialDNA,FinalDNA,InitialAA,FinalAA,Codon,Reference
cagCCTcat,CCC,Pro,Pro,P68P,Windl(1999)HumGen105:244.
aagCCGagt,CTG,Pro,Leu,P102L,Hsiao(1989)Nature338:342.
aagCCAaaa,CTA,Pro,Leu,P105L,Kitamoto(1993)BBRC191:709.
aagCCAaaa,ACA,Pro,Thr,P105T,personalcommunication13
gcaGCAagc,GTA,Ala,Val,A117V,Doh-Ura(1989)BBRC163:974.
gcaGCAagc,GCG,Ala,Ala,A117A,Hsiao(1989)Nature338:342
gggGGCctt,GGG,Gly,Gly,G124G,[Prusiner(1997)Science278:245]
tacATGctg,GTG,Met,Val,M129V,Doh-Ura(1989)BBRC163:974.
cccATCata,ATG,Ile,Met,I138M,Laplanche(2000)pers.comm.
ttcGGCcag,AGC,Gly,Ser,G142S,Laplanche(2000)pers.comm.
gacTATgag,TAG,Tyr,stop,Y145s,Ghetti(1996)PNAS93:744
aacCAAgtg,TAA,Gln,stop,Q160s,FinckhU(2000)AmJHumGenet66:110
caaGTGtac,GTA,Val,Val,V161V,Prusiner(1997)Science278:245
agcAACcag,AGC,Asn,Ser,N171S,Samaia(1997)Nature390:241
cagAACaac,AAT,Asn,Asn,N173N,Laplanche(2000)pers.comm.
gtgCACgac,CAT,His,His,H177H,Ripoll(1993)Neurology43:1934
cacGACtgc,AAC,Asp,Asn,D178N,Goldfarb(1991)Lancet337:425
tgcGTCaat,ATC,Val,Ile,V180I,Kitamoto(1993)BBRTC191:709
atcACAatc,GCA,Thr,Ala,T183A,Nitrini(1997)AnnNeurol42:138
cagCACacg,CGC,His,Arg,H187R,Cervenakova(1999)AmJMedGenet88(6):653
cacACGgtc,AGG,Thr,Arg,T188R,Windl(1999)HumGen105.244
cacACGgtc,AAG,Thr,Lys,T188K,FinckhU(2000)AmJHumGenet66:110
cacACGgtc,GAG,Thr,Ala,T188A,CollinsS(2000)Arch.Neurol57:1058
cacACGgtc,ACA,Thr,Thr,T188T,Laplanche(2000)pers.comm.
gggGAGaac,AAG,Glu,Lys,E196K,Peoc'h(2000)HumanMutation#323
aacTTCacc,TCC,Phe,Ser,F198S,Hsiao(1992)NatureGenet.1:68
accGAGacc,AAG,Glu,Lys,E200K,Goldgaber(1989)Exp.Neurol.106:204.
accGACgtt,AAC,Asp,Asn,D202N,Piccardo(1998)JNExpNeur57:979
accGACgtt,GAT,Asp,Asp,D202D,Laplanche(2000)pers.comm.
gacGTTaag,ATT,Val,Ile,V203I,Peoch(2000)HumanMutation#323
gagCGCgtg,CAG,Arg,His,R208H,Mastrianni(1996)Neurol.47:1305
gagCGCgtg,CGT,Arg,Arg,R208R,Laplanche(2000)pers.comm.
gtgGTTgag,ATT,Val,Ile,V210I,Pocchiari(1993)Ann.Neurol.34:802.7
gttGAGcag,CAG,Glu,Gln,E211Q,Peoch(2000)HumanMutation#323
gagCAGatg,CGG,Gln,Pro,Q212P,Piccardo(1998)JNExpNeur57:979
gagCAGatg,CAA,Gln,Gln,Q212Q,Windl(1999)HumGen105.244.
accCAGtac,CGG,Gln,Arg,Q217R,Hsiao(1992)NatureGenet.1:68.
tacGAGagg,AAG,Glu,Lys,E219K,Barbanti(1996)Neurobiology47:734
cagAGAgga,AGG,Arg,Arg,R228R,Windl1999HumGen105.244.
ggaTCGagc,TCA,Ser,Ser,S230S,Windl(1999)HumGen105.244.
agcATGgtc,AGG,Met,Arg,M232R,Kitamoto(1993)BBRC191:709.
tctCCAcct,TCA,Pro,Ser,P238S,Windl(1999)HumGen105.244